The mitochondrial 12S rRNA gene encodes the 16-amino acid peptide known as MOTS-c (Mitochondrial ORF of the 12S rRNA Type-C). Unlike most other peptides, the manufacturer of the product- aasraw produces them from mitochondrial DNA (mtDNA) rather than nuclear DNA, which makes it special. It was identified in 2015 and is a member of the expanding class of mitochondrial-derived peptides (MDPs), which function as signaling molecules to control metabolic and cellular processes.
Key Functions of MOTS-c- Aasraw
It improves insulin sensitivity, glucose metabolism, and metabolic regulation, which may help with diseases including type 2 diabetes, obesity, and metabolic syndrome. MOTS-c and BPC 157 help maintain cellular homeostasis, lower oxidative stress, and increase cellular viability in metabolic stress. By stimulating pathways like AMPK (AMP-activated protein kinase), it replicates the effects of physical exercise. This is known as exercise mimetic. It is an ideal anti-aging and longevity supplement that has been related to better mitochondrial activity and longer lifespans in model species. Its numerous anti-inflammatory qualities have been shown to lessen inflammation and guard against metabolic diseases linked to ageing. Buy MOTS-c to enhance your bone density and muscle function.
The peptide mainly controls metabolic and cellular stress responses by interfering with nuclear pathways. Energy homeostasis depends on the activation of the AMPK Pathway (AMP-activated protein kinase). It stimulates fatty acid oxidation and improves glucose absorption via activating AMPK. Additionally, it suppresses the mTOR Pathway, which is involved in cell growth and metabolism and is the mTOR-mechanistic target of rapamycin. MOTS-c aids in the body’s adaptation to metabolic stress by downregulating mTOR. It facilitates nuclear translocation; when under stress, it can also can go to the nucleus and change gene expression to increase metabolic flexibility.
Physiological and Therapeutic Effects
It increases skeletal muscle glucose absorption and insulin sensitivity. Mots-c enhances muscle performance and endurance, simulating the benefits of exercise. It improves energy output by boosting mitochondrial biogenesis. According to new research, this particular peptide may prevent neurodegenerative illnesses by lowering oxidative stress and inflammation. By controlling cell division, it may alter immunological responses and potentially have anti-cancer effects. It can be difficult to keep the drug more stable and bioavailable in the body, just like other peptides. To determine the optimal dosage and long-term safety in humans, more research is required. Individualized strategies about aasraw might be necessary because mitochondrial function varies with age, sex, and heredity. It is one of the best peptides one can take on for the best and healthier lifestyle.
